We also found positive correlations between PD-L1 overexpression and advanced tumours, females, non-smokers, non-drinkers and high levels of tumour PD-1, CD4, and CD8.ī7-H1 antigen Immunohistochemistry Meta-analysis Mouth neoplasms Prognosis Programmed death ligand 1 Squamous cell carcinoma of head and neck.Ĭopyright © 2020 Elsevier Ltd. behavioral therapies (n9 Hedges g-.07) or pharmacological treatments (n3 Hedges g.13).
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This meta-analysis found a worse prognosis in OSCCs overexpressing PD-L1 in the cell membrane as measured by disease specific survival and disease-free survival. Mindfulness-based therapy: a comprehensive meta-analysis. Nevertheless, a meta-analysis involving 974 pregnant women from 10. The results obtained using the total data (HR 0.875, 95 CI 0.7840.976. studied GFR estimation in a cohort of 209 women with preeclampsia. Analysis of studies measuring PD-L1 expression in the cell membrane showed a worse prognosis for disease-specific survival (HR = 1.74, 95% CI = 1.14-2.66, p = 0.01) and disease-free survival (HR = 1.56, 95% CI = 1.16-2.09, p = 0.003). A comprehensive meta-analysis of relevant studies, RNA-seq data, and microarray expression profiles was conducted to analyze the prognostic value of miR-146a-5p in solid cancers. Meta-analysis was performed for survival outcomes and clinic-pathological parameters.Ģ6 articles were included comprising 2532 patients. Study quality was assessed using the QUIPS tool.
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Studies measuring PD-L1 levels by immunohistochemistry (IHC) in OSCC were included. PubMed, Embase, Web of Science, and Scopus were searched for studies published on or before March 02, 2019.
#Comprehensive meta analysis 3 download
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#Comprehensive meta analysis 3 software
To review the scientific evidence of a prognostic role for PD-L1 levels in OSCC. Download Comprehensive Meta Analysis 3.3.070 from our software library for free.
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The presence of Programmed Death-Ligand 1 protein (PD-L1) in oral squamous cell carcinoma (OSCC) may indicate an ability to evade immune response and has been suggested as a prognostic marker, but there is controversy in the literature.